My main research interest lies in RNA Virus Evolution, mainly the fascinating concept of viral quasispecies and how viral population dynamics plays in the generation of fitness landscapes. Moreover, I´m interested in the combination between experimental and computational techniques to study molecular epidemiology and evolution at the genomic level of RNA viruses.
B.S., 2005, Biology Universidad de la República, Montevideo, URUGUAY
M.Sc., 2008, Molecular and Cell Biology Universidad de la República- PEDECIBA, Montevideo, URUGUAY
Ph.D., 2012, Virology Universidad de la República- PEDECIBA- Institut Pasteur de Montevideo, URUGUAY
Post Doctoral Fellow, 2012-present Department of Virology, Institut Pasteur, Paris, France
I am studying the population dynamics of arbovirus infection, using chikungunya virus as a model, both in tissue culture and in vivo. My project involves exploring how the host environment influences virus evolution and using fidelity variants of chikungunya virus, how the virus reacts to changes in selective pressures.
B.S., 2010, Biology Barnard College, Columbia University, New York, NY
Fullbright Scholar, 2011 Duke-National University of Singapore Graduate Medical School
PH.D Student, 2011, Virology Pasteur Institute/University Paris VII International Ph.D. program
Research Interests My research interests involve understanding the detailed molecular mechanisms required for RNA virus pathogenesis. In particular, I am interested in the dynamic host-pathogen interactions involved in these processes. My projects in the lab will focus on the role of genetic variability in arbovirus pathogenesis.
B.S., 2003, Biochemistry University of Delaware - Newark, DE USA
Ph.D., 2009, Cellular and Molecular Biology University of Michigan - Ann Arbor, MI USA
Post-doctoral associate, 2009-2011 Yale University - New Haven, CT USA
Post Doctoral Fellow, 2011 Virology, Institut Pasteur, Paris, France
My main interests are RNA virus evolution and Immunology. As part of my research, I study how viral population fluctuations, involving transmission and founder events, shape virus evolution. I am also interested in understanding the response of the immune cells, mainly Dendritic Cells, against virus infections and how the virus evolves to escape the immune system.
B.S., 2000, Biology Universidad de Valencia, Burjassot, Valencia, SPAIN
Ph.D., 2007, Molecular Biology Universidad Autonoma de Madrid, Madrid, Madrid, SPAIN
Post Doctoral Fellow, 2007, Human Immunology Mount Sinai School of Medicine, New York, New York, USA
Post Doctoral Fellow, 2010-present Department of Virology, Institut Pasteur, Paris, France
Degree from the Ecole Pratique des Hautes Etudes, La Sorbonne, 2000 Biomedical Research Specialization Degree option virology, 1998 Diploma of technical biochemistry, 1997
Research Technician, 2006-07 Apoptosis and Immune System Group, Department of Immunology, Institut Pasteur (Susin lab)
Research Assistant, 2000-2006 Department of Clinical Science at South Bristol, Henry Wellcome Laboratories for Integrative Neuroscience and Endocrinology, University of Bristol, United Kingdom (Murphy lab)
HIV technician, 2000 Virology department, teaching hospital Henri Mondor, Creteil, France (Pawlotsky lab)